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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
12.5 DPC

7 matching records from 7 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Edar  ectodysplasin-A receptor  
Results  Reference
1J:152420 Denaxa M, Sharpe PT, Pachnis V, The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Dev Biol. 2009 Sep 15;333(2):324-36
1*J:73357 Headon DJ, Emmal SA, Ferguson BM, Tucker AS, Justice MJ, Sharpe PT, Zonana J, Overbeek PA, Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature. 2001 Dec 20-27;414(6866):913-6
1*J:67054 Laurikkala J, Mikkola M, Mustonen T, Aberg T, Koppinen P, Pispa J, Nieminen P, Galceran J, Grosschedl R, Thesleff I, TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelial signaling centers and is regulated by Wnt and activin during tooth organogenesis. Dev Biol. 2001 Jan 15;229(2):443-55
1J:107400 Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I, p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development. 2006 Apr;133(8):1553-63
1J:111052 Mou C, Jackson B, Schneider P, Overbeek PA, Headon DJ, Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9075-80
1*J:231699 Voutilainen M, Lindfors PH, Trela E, Lonnblad D, Shirokova V, Elo T, Rysti E, Schmidt-Ullrich R, Schneider P, Mikkola ML, Ectodysplasin/NF-kappaB Promotes Mammary Cell Fate via Wnt/beta-catenin Pathway. PLoS Genet. 2015 Nov;11(11):e1005676
1J:164212 Wells KL, Mou C, Headon DJ, Tucker AS, Recombinant EDA or Sonic Hedgehog rescue the branching defect in Ectodysplasin A pathway mutant salivary glands in vitro. Dev Dyn. 2010 Oct;239(10):2674-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory